Cryosupernatant
The term cryosupernatant refers to plasma from which the cryoprecipitate has been removed. It is used to treat thrombocytopenic purpura.Components
The resulting plasma has reduced levels of factor VIII, von Willebrand factor, factor XIII, fibronectin and fibrinogen. While the levels of FVIII are greatly reduced, levels of fibrinogen can be as much as 70% of original levels.Uses
Cryosupernatant plasma can be used when replacement of FVIII is not required, and is indicated for plasma exchange for patients with thrombotic thrombocytopenic purpura as well as for treatment of hemolytic-uremic syndrome by plasma exchange, when plasma exchange is indicated.
