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Cytochrome P450 eryF
6-deoxyerythronolide B
hydroxylase
is an
Actinobacteria
Cytochrome P450
enzyme
originally from
Saccharopolyspora
erythraea
,
catalyzes
the 6S-hydroxylate of 6-deoxyerythronolide B to
erythronolide B
which is the first
step
of
biosynthesis
of the
macrolide antibiotic
erythromycin
. This
bacterial
enzyme
belongs to
CYP family
CYP107, with the
CYP
Symbol
CYP107A1
.