Cytopenia


Cytopenia is a reduction in the number of mature blood cells. It is common in cancer patients being treated with radiation and/or chemotherapy.

Types

Anemia - a reduction of the red blood cells in the body.
Leukopenia - a deficiency of white blood cells, or leukocytes
Neutropenia - a type of leukopenia, with a specific deficiency in neutrophils
Thrombocytopenia - a deficiency of platelets
Pancytopenia - When all three types of blood cells; red blood cells, white blood cells, and platelets, are all deficient. This is a life-threatening disorder that is a characteristic of aplastic anemia.
There are also two general types of cytopenia: autoimmune and refractory.
Autoimmune cytopenia - caused by an autoimmune disease when your body produces antibodies to destroy the healthy blood cells.
Refractory cytopenia - caused by bone marrow not producing healthy blood cells, and can be a result of cancer.

Symptoms and signs

The symptoms of cytopenia vary depending on what type is diagnosed.
The symptoms of anemia include:
The symptoms of leukopenia include:
The symptoms of thrombocytopenia include:
Cytopenias are caused by anything that promotes the body into creating antibodies to fight blood cells. This includes, but is not limited to,:
The treatments for cytopenia vary depending on the type of cytopenia. The treatment for anemia is rest and a diet consisting of high iron foods. Medication can also be used such as:
People with thrombocytopenia can be treated by avoiding skin damage such as bruising or breaking of the skin.
Neutropenia patients are advised to avoid contact with people who are ill, monitor closely for signs of infection, and take antibiotics when appropriate.
Growth factors are also another way to treat cytopenia. Growth factors are synthetic versions of substances involved in stimulating red and white blood cell production. These medications include:
Bone marrow and stem cell transplantation are effective for all types of cytopenias. However, when a compatible donor cannot be found, immunosuppressive therapy is also common. Antilymphocyte globulin or antithymocyte globulin is mixed with cyclosporine to promote cell growth.