Born Derrick Jones, he was born and raised in the neighborhood of Harlem in the Manhattan borough of New York City. He later moved to The Bronx as a teenager. At age 15, it was there that he met Scott La Rock and later formed Boogie Down Productions along with KRS-One in 1986. In his early career with the group, he was given the nicknames as "the Human TR-808" and "the 808". D-Nice also gained significant popularity when he produced the "Self-Destruction" song for the Stop the Violence Movement. Soon after the song released, D-Nice signed a solo deal Jive Records and released his debut studio album called "Call Me D-Nice" in 1990. The album peaked at #75 on the Billboard Top Pop Albums and #12 on the Billboard Top Black Albums chart. It was also rated 3.5 out of 5 mics by The Source magazine. In 1991, D-Nice released his second studio album called "To tha Rescue". The album peaked at #137 on the Top Pop Albums chart and #27 on the Top R&B Albums chart. He collaborated with KRS-One, Naughty by Nature, and Too Short for the album. D-Nice clashed with Jive Records over his stylistic direction and soon stopped releasing music as a recording artist. In 1996, he had his first daughter named Ashli Lyric Jones D-Nice became a web developer in the late '90s and started his own creative services company in 2000. He later had another daughter named Dylan Coleman-Jones with Kelli M. Coleman, Executive Vice President for GlobalHue. D-Nice began working as a photographer in the 2000s while also still being a DJ and shot the album covers for Carl Thomas' 2007 album So Much Better and Pharoahe Monch's 2011 album W.A.R. . He also photographed the album cover for Kenny Lattimore's 2017 album, Vulnerable. . In August 2008, he married actress Malinda Williams, but the couple separated in October 2009. In February 2010, the couple filed for divorce and the divorce was finalized on June 14, 2010. In March 2020, D-Nice began hosting Homeschool at Club Quarantine on Instagram Live from his home as a way for people to come together and help others cope with the COVID-19global health crisis. The 3/21 Saturday night dance party ran 9 hours and D-Nice urged people to "take care of one another and wash their hands." It drew over 100,000 viewers, including Rihanna, Lenny Kravitz, Nile Rodgers, Lalah Hathaway, Bernie Sanders, Joe Biden, Dwyane Wade, Janet Jackson, Fab Five Freddy, Michelle Obama, Mark Zuckerberg, Donnie Wahlberg, Angela Bassett and Sheila E. among others. The following day, March 22, his stream capped at over 150,000 simultaneous viewers. D-Nice won the 2020 Webby Artist of the Year in the category Special Achievement. He also was one of the Honoree Recipients for the "Shine A Light" Award during the 2020 BET Awards for his contributions of Club Quarantine, alongside co-recipients with VERZUZ creators Timbaland and Swizz Beatz.