David MacMillan


David William Cross MacMillan is a Scottish-born chemist and the James S. McDonnell Distinguished University Professor of Chemistry at Princeton University, where he was also the Chair of the Department of Chemistry from 2010 to 2015.

Education and early life

MacMillan was born in Bellshill, Scotland in 1968. He received his undergraduate degree in chemistry at the University of Glasgow, where he worked with Ernie Colvin.
In 1990, he left the UK to begin his doctoral studies under the direction of Professor Larry Overman at the University of California, Irvine. During this time, he focused on the development of new reaction methodology directed toward the stereocontrolled formation of bicyclic tetrahydrofurans. MacMillan's graduate studies culminated in the total synthesis of 7--deacetoxyalcyonin acetate, a eunicellin deterpenoid isolated from soft coral Eunicella stricta.

Career and research

Upon receiving his Ph.D., MacMillan accepted a position with Professor David Evans at Harvard University. His postdoctoral studies centered on enantioselective catalysis, in particular, the design and development of Sn-derived bisoxazoline complexes.
MacMillan began his independent research career as a member of the chemistry faculty at the University of California, Berkeley in July 1998. He joined the department of chemistry at Caltech in June 2000, where his group's research interests centered on new approaches to enantioselective catalysis. In 2004, he was appointed as the Earle C. Anthony Professor of Chemistry. For personal reasons, he moved to Princeton University in September 2006.
MacMillan's research group has made many advances in the field of asymmetric organocatalysis, and they have applied these new methods to the synthesis of a range of complex natural products.
Between 2010 and 2014, Professor MacMillan was the founding Editor-in-Chief of the journal Chemical Science, the flagship general chemistry journal published by the Royal Society of Chemistry.

Honours and awards