Lesher was born August 4, 1903, the son of Margaret and David Lesher, in Williamsport, Maryland. His first business experience began when he opened a small ice cream stand at the age of 10. When he was 12, he gave that up for a job in a local tannery partially owned by his father. In his high school years Lesher found work as a railroad waybill clerk and was active in sports, playing football, baseball, and soccer. He attended the University of Maryland, graduating magna cum laude, and proceeded to earn a law degree from Harvard University. He was married to Kathryn Lesher who would die of cancer in 1971. He was later remarried to Margaret Lesher until his death in 1993 at the age of 90. In 1997 Margaret Lesher drowned under mysterious circumstances in Bartlett Lake in Arizona while on a camping trip with her husband of six months Collin "T.C." Thorstenson.
Newspapers
Though he had a successful legal practice in Kansas City, Missouri, Lesher grew bored with law and found himself fascinated with newspapers, especially their ability, in his view, to shape and improve a community. Initially, he acquired a small paper in Nebraska but he found no way to generate a profit. In 1941, at the age of 39 Lesher and his family moved to California where he purchased a small daily, the Merced Sun-Star. While the local economy was booming with the war effort, civilian rationing meant empty store shelves and little to no advertising revenues. Lesher invited some prominent local business owners to dinner and asked them to advertise for the sake of the area paper. In this way, he solidified the paper's financial position. After the war, Lesher sought other opportunities and found them in Contra Costa County. Shortly after buying the Walnut Creek Journal-Courier in 1947, he renamed it the Contra Costa Times to reflect its growing primacy in the region. Readers of the Times referred to it as "the green sheet" because the cover page was printed on green newsprint. Even though the Times was delivered without a subscription Lesher had his delivery people make a monthly attempt to collect delivery fees from readers. Over time, he purchased other papers in the region and pioneered a series of new subscription tactics including both "controlled circulation" and a gradual shift from free weekly to paid daily papers. In 1977, the California Press Association awarded Lesher with its Publisher of the Year award. In 1983, President Ronald Reagan presented Lesher with the highest award granted by the National Newspaper Association for distinguished leadership.