Work was selected among thirteen contestants for the third season of RuPaul's Drag Race, which was announced on January 24, 2011. During the season, she impersonated Cher for the "Snatch Game" episode, where contestants were required to imitate a chosen celebrity. Bowen Yang wrote "Delta barely made an attempt at all... Points for the wink at Bob Mackie with her look, but otherwise Delta just waded around in her nothing-doing. Snap out of it!" She placed seventh overall, losing a lip sync performance to Manila Luzon on Donna Summer's "MacArthur Park". Out called the battle "certainly one of the most famous lip syncs" of the show. Outside of season three, she was an audience member for the season five and season six reunions, and was a guest with other Drag Race alumni for the first challenge of season ten. Villarreal became RuPaul's personal wig stylist for her judging panel attire beginning with the second episode of the ninth season, with season two alumnus Raven styling her makeup. Work appeared as a guest for the first challenge in the premiere of season eleven.
Post ''Drag Race''
Villarreal appeared on a 2011 episode of E!'s The Soup with RuPaul, Raja, and Shangela. She makes recurring appearances on WoWPresent's internet showFashion Photo Ruview, filling in for Raja or Raven to critique looks from Drag Race alumni, with her first appearance on November 19, 2014. She also makes regular appearances on the web showThe Pit Stop, which reviews the episodes of Drag Race. She was on its debut episode on August 27, 2016. Work appeared on the cover of Skorch Magazine in 2013. In August 2015, she headlined Palouse Pride in Moscow, Idaho. On August 6, 2016, she was invited on stage by Adele in a Los Angeles concert, while in full drag as an Adele impersonator. They took a selfie, which quickly went viral. Villarreal received the Primetime Emmy Award for Outstanding Hairstyling for a Multi-Camera Series or Special at the 70th Primetime Creative Arts Emmy Awards for his work. She portrayed Adele in the music video for Taylor Swift's "You Need to Calm Down".
Music
Delta Work released her debut single, "The Walkin' Blues ", on May 12, 2015. She also was part of the group The Heathers, with Manila Luzon, Raja, and Carmen Carrera. The group released their debut single "Lady Marmalade" on June 6, 2014.