Dihydrodeoxycorticosterone


5α-Dihydrodeoxycorticosterone, also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone by the enzyme 5α-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects.

Chemistry