Dihydropyridine
Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond. They are particularly well known in pharmacology as L-type calcium channel blockers, used in the treatment of hypertension. Compared with certain other L-type calcium channel blockers that have significant action at the heart, they are relatively vascular selective in their mechanism of action in lowering blood pressure.
Class members
Dihydropyridine class L-type calcium channel blockers include, in alphabetical order :| Name | Image | Brand name |
| Amlodipine | Norvasc, Istin, Normodipine, Tenox, Cordi Cor | |
| Aranidipine | Sapresta | |
| Azelnidipine | CalBlock | |
| Barnidipine | Vasexten, Libradin, Cyress, HypoCa | |
| Benidipine | Coniel | |
| Cilnidipine | Atelec, Cilacar, Cinalong, Siscard | |
| Clevidipine | Cleviprex | |
| Cronidipine | ||
| Darodipine | ||
| Dexniguldipine | ||
| Efonidipine | Landel | |
| Elgodipine | ||
| Elnadipine | ||
| Felodipine | Renedil, Plendil | |
| Flordipine | ||
| Furnidipine | ||
| Iganidipine | ||
| Isradipine | DynaCirc CR | |
| Lacidipine | Lacipil, Motens, Sakure | |
| Lemildipine | ||
| Lercanidipine | Zanidip, Zanidip-Recordati | |
| Levamlodipine | EsCordi Cor | |
| Levniguldipine | ||
| Manidipine | Manyper, Caslot, Madipine | |
| Nicardipine | Cardene, Cardene SR | |
| Nifedipine | Adalat, Nifedical, Procardia, Corinfar, Cordaflex | |
| Niguldipine | ||
| Niludipine | ||
| Nilvadipine | Nivadil | |
| Nimodipine | Nimotop | |
| Nisoldipine | Sular, Baymycard, Syscor | |
| Nitrendipine | Baypress, Cardif, Nitrepin, Baylotensin | |
| Olradipine | ||
| Oxodipine | ||
| Palonidipine | ||
| Pranidipine | Acalas | |
| Ryodipine | ||
| Sagandipine | ||
| Sornidipine | ||
| Teludipine | ||
| Tiamdipine | ||
| Trombodipine | ||
| Vatanidipine |
The pharmaceutical drug finerenone is also a dihydrophyridine derivative, but does not act as a calcium channel blocker but as an antimineralocorticoid.