Dihydroxy-acid dehydratase
In enzymology, a dihydroxy-acid dehydratase is an enzyme that catalyzes the chemical reaction
Hence, this enzyme has one substrate, 2,3-dihydroxy-3-methylbutanoate, and two products, 3-methyl-2-oxobutanoate and H2O.
This enzyme participates in valine, leucine and isoleucine biosynthesis and pantothenate and coenzyme A biosynthesis.Nomenclature
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2,3-dihydroxy-3-methylbutanoate hydro-lyase. Other names in common use include
- acetohydroxyacid dehydratase,
- alpha,beta-dihydroxyacid dehydratase,
- 2,3-dihydroxyisovalerate dehydratase,
- alpha,beta-dihydroxyisovalerate dehydratase,
- dihydroxy acid dehydrase,
- DHAD,
- and 2,3-dihydroxy-acid hydro-lyase.
