Doe Run, Missouri
Doe Run is an unincorporated community and census-designated place in St. Francois County, Missouri, United States. It is located on Routes 221 and B, approximately three miles southwest of Farmington.History
Doe Run had its start in the 1880s as a lead-mining town. A post office called Doe Run has been in operation since 1887. The community takes its name from nearby Doe Run Creek.
