Charlesworth was appointed by the British Committee on Ancient Glass to undertake the British census of ancient glass, which was completed in 1955 although its publication was prevented by the committee's lack of funds. In 1965 she joined the Egypt Exploration Society’s excavations at Buto, taking part in each season's excavation until it ended in 1969. At Buto she supervised the excavation of the furnace site, and published her findings. While in Cairo she recorded the working of a local 'primitive' glass furnace, comparing its functioning with that of a contemporary furnace at Damascus, and with medieval glasshouse furnaces in Britain. In the final year of excavations at Buto she became field director, taking over from Veronica Seton-Williams. Alongside her work in Egypt, she continued to work with Donald Benjamin Harden, publishing a summary of his catalogue for the 1969 British Museum exhibition Masterpieces of Glass. Once the excavations at Buto had concluded, Charlesworth focused on her work within Britain. She first held a Leverhulmeresearch fellow at the Museum of London, before serving as Inspector of Ancient Monuments. Under these auspices she directed excavations within northern Britain, notably Carlisle, where she discovered the south gate and rampart of the Roman fort in Carlisle, finally locating the fort's exact position. Here she discovered surviving timbers that could be dated by dendrochronology, and shown to have been felled in the autumn or winter of AD72/3. These offered new evidence in the debate over the chronology of the Roman conquest of northern Britain, which may have been under Petillius Cerialis, or Agricola. At Housesteads she excavated the Commandant's house and the hospital with John Wilkes in the late 1960s and 1970s. She also excavated Carrawburgh fort, Hadrian's Wall turret 51A in 1970 34A in 1971, and 29A. Excavation of Hadrian's Wall at Walton was carried out under her direction in the 1970s. Charlesworth was one of the founding members of the Association for the History of Glass in 1978, and served as its Secretary from 1979-1981. As well as her expert contributions to the study of ancient glass, she also wrote for a more general readership, contributing to guidebooks, e.g., for the museum at the Roman site of Wall in Staffordshire, Aldborough Roman town and Museum, Yorkshire and Hardknott Fort. A memorial lecture was held in her name by the Cumberland and Westmorland Archaeological Society in 1982.
Publications
Charlesworth, Dorothy Excavations on the Carrawburgh car park site, 1964. in Archaeologia Aeliana, 1-16
Charlesworth, Dorothy. . Journal of Glass Studies. 13: 34–37.
Charlesworth, D. "The commandant's house, Housesteads". Archaeologia Aeliana.
Charlesworth, D. . Archaeological Journal. 135
Charlesworth, Dorothy. 'Notice of book: BRITISH MUSEUM. Masterpieces of glass. By D. B. Harden and others,' in The Journal of Hellenic Studies, Vol. 89, pp. 191–192. https://www.jstor.org/stable/627535
Charlesworth, Dorothy; Thornton, J. H.. 'Leather Found in Mediobogdum, the Roman Fort of Hardknott. Britannia. 4: 141–152. doi:. JSTOR
Erim, K.T.; Reynolds, Joyce; White, K.D.; Charlesworth, Dorothy. 1973, 'The Aphrodisias Copy of Diocletian's Edict on Maximum Prices,' in JRS' doi:. JSTOR