Duffie
Duffie or Duffié may refer to:
- Alfred N. Duffié, French-American soldier and diplomat who served in the Crimean War and the American Civil War
- Darrell Duffie, Canadian economist
- Grace Duffie Boylan, American writer
- John Duffie, former pitcher in Major League Baseball
- Kieran Duffie, professional Football player
- Matt Duffie, professional rugby league player
- Paul Duffie, former politician, lawyer and judge in the Canadian province of New Brunswick
- William R. Duffie, forestry engineer and political figure in New Brunswick, Canada