Dyslipidemia


Dyslipidemia is an abnormal amount of lipids in the blood. In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle. Prolonged elevation of insulin levels can also lead to dyslipidemia. Likewise, increased levels of O-GlcNAc transferase may cause dyslipidemia.

Types

Diagnosis

Classification

Physicians and basic researchers classify dyslipidemias in two distinct ways:
Fredrickson Classification:
PhenotypeIIIaIIbIIIIVV
Elevated LipoproteinChylomicronLDLLDL and VLDLIDLVLDLVLDL and chylomicrons

Screening

Testing the general population under the age of 40 without symptoms is of unclear benefit.

Management