Voit is recognized as a leading expert in complex biomedical systems modeling and, in particular, the scientific modeling and systems analysis framework of Biochemical Systems Theory Voit's team has been developing numerous methodologies within BST and using these, along with other modeling techniques, to analyze biomedical phenomena from microbial dynamics and bacterial metapopulations to diseases like schizophrenia and malaria. He has also worked in the areas of computational statistics and metabolic engineering. Voit has documented these advancements in about 300 scientific journal articles and book chapters. He is also the author of several books, some with translations into Chinese and Korean, an introductory text for undergraduate and graduate students, and The Inner Workings of Life: Vignettes in Systems Biology a non-technical introduction to systems biology for educated non-experts.
Selected publications
Voit, E.O. : ‘’Canonical Nonlinear Modeling. S-System Approach to Understanding Complexity‘’, xi+365 pp., Van Nostrand Reinhold, NY, 1991.
Voit, E.O., and T. Radivoyevitch: Biochemical systems analysis of genome-wide expression data, ‘’Bioinformatics ‘’ ‘’’16 ‘’’, 1023-1037, 2000.
Voit, E.O., and J.S. Almeida: Decoupling dynamical systems for pathway identification from metabolic profiles. ‘’Bioinformatics‘’ ‘’’20 ‘’’,1670-1681, 2004.
Alvarez-Vasquez, F., K. J. Sims, L.A. Cowart, Y. Okamoto, E. O. Voit, and Y. A. Hannun. Simulation and evaluation of de novo sphingolipid fluxes in S. cerevisiae. ‘’Nature ‘’ ‘’’433 ‘’’, 425-430.
Voit, E.O., A.R. Neves, and H. Santos. The intricate side of systems biology. ‘’Proc. Nat. Acad. Sci. ‘’, ‘’’103 ‘’’, 9452-9457, 2006.
Goel, G., I-C. Chou, and E.O. Voit: System estimation from metabolic time series data. ‘’Bioinformatics ‘’ ‘’’24 ‘’’, 2505-2511, 2008.
Voit, E.O., W.C. Newstetter, and M.L. Kemp: A feel for systems, ‘’Mol. Syst. Biol. ‘’ ‘’’8 ‘’’, 609, 2012.
Voit, E.O., H.A. Martens, and S.W. Omholt: 150 years of the mass action law. ‘’PLoS Comp. Biol. ‘’ ‘’’11 ‘’’: e1004012, 2015.
Faraji, M. and E.O. Voit: Nonparametric dynamic modeling. ‘’Math. Biosc. ‘’ ‘’’287 ‘’’, 130-146, 2017.
Voit, E.O.: The best models of metabolism. ‘’WIREs Systems Biology and Medicine‘’ 2017, e1391.
Voit, E.O.: ‘’Systems Biology: A Very Short Introduction‘’, Oxford University Press, Cambridge, U.K., 2019.
Voit, E.O., Perspective: Dimensions of the scientific method.‘’PLoS Comp. Biol. ‘’ ‘’’15 ‘’’: e1007279, 2019.
Books
Voit, E.O.: Computational Analysis of Biochemical Systems. A Practical Guide for Biochemists and Molecular Biologists, xii + 530 pp., Cambridge University Press, Cambridge, U.K., 2000.
Torres, N.V., and E.O. Voit: Pathway Analysis and Optimization in Metabolic Engineering. Cambridge University Press, Cambridge, U.K., 2002.
Voit, E.O.: A First Course in Systems Biology. Garland Science, New York, NY, 2012, xiv+445pp.
Voit, E.O.: The Inner Workings of Life. Vignettes in Systems Biology, xii + 210 pp., Cambridge University Press, Cambridge, U.K., 2016.
