Blake soon abandoned the study of law at the request of his uncle, Eli Whitney, who desired his assistance in erecting and organizing the gun factory at Whitneyville. Here he made important improvements in the machinery and in the processes of manufacturing arms. On the death of his uncle in 1825, Blake associated with himself his brother Philos, and continued to manage the business. In 1836 they were joined by another brother, John A., and, under the firm name of Blake Brothers, established at Westville a factory for the production of door locks and latches of their own invention. The business was afterward extended so as to include casters, hinges, and other articles of hardware, most of which were covered by patents. In this branch of manufacture, Blake Brothers were among the pioneers, and long held the front rank. In 1852, Blake was appointed to superintend the macadamizing of the city streets, and his attention was directed to the want of a proper machine for breaking stone. This problem he solved in 1857, by the invention of the Blake stone breaker, which, for originality, simplicity, and effectiveness, was justly regarded by experts as unique. Blake was one of the founders, and for several years president, of the Connecticut Academy of Science. He contributed valuable papers to the American Journal of Science and other periodicals, the most important of which he published in a single volume as Original Solutions of Several Problems in Aërodynamics.
Personal life
On July 8, 1822, Blake was married to Eliza Maria O'Brien, a daughter of Edward J. O'Brien and Mary O'Brien, a great-granddaughter of the Rev. James Pierpont, one of the founders of Yale College. After the death of Eliza's father, her mother remarried to prominent lawyer Eleazer Foster and had several more children, including Eleazer Kingsbury Foster. Together, Eli and Eliza were the parents of many children, including five boys who graduated from Yale:
Charles Thompson Blake, who went to California during the gold rush and worked in gold assaying for Wells, Fargo & Co. He married Harriet Waters Stiles.
Henry Taylor Blake, who married Elizabeth Coit Kingsley, daughter of James Luce Kingsley.
Frances Louisa Blake, who married Arthur Dimon Osborn, son of U.S. Representative Thomas Burr Osborne. Arthur's sister Elizabeth married Gov. Henry Baldwin Harrison.
Eli Whitney Blake, Jr., who married Helen Mary Rood.
James Pierrepont Blake, who drowned near Beaufort, South Carolina while trying to assist freedmen.
Eliza Maria Blake.
His wife died on April 15, 1876 and Blake died on August 18, 1886 in New Haven, Connecticut.
Descendants
Through his daughter Mary, he was the grandfather of four, including homemaker Dotha Bushnell and Mary Pierpont Bushnell, who married Rowland Gibson Hazard , the parents of Rowland Hazard III, a founder of Alcoholics Anonymous. Through his daughter Frances, he was the grandfather of chemist Thomas Burr Osborn and Arthur Sherwood Osborn.
