Epsilonpapillomavirus


Epsilonpapillomavirus is a genus of viruses, in the family Papillomaviridae. Cattle serve as natural hosts and it is one of the bovine papillomaviruses. There are currently two species in this genus, including the type species Epsilonpapillomavirus 1. Diseases associated with this genus include: fibropapillomas and true epithelial papillomas of the skin.

Taxonomy

Group: dsDNA

Structure

Viruses in Epsilonpapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
EpsilonpapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Bovine serve as the natural host. Transmission routes are contact.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
EpsilonpapillomavirusBovinesEpithelial: skinCell receptor endocytosisLysisNucleusNucleusContact