Estradiol phosphate
Estradiol phosphate, or estradiol 17β-phosphate, also known as estra-1,3,5-triene-3,17β-diol 17β-, is an estrogen which was never marketed. It is an estrogen ester, specifically an ester of estradiol with phosphoric acid, and acts as a prodrug of estradiol in the body. It is rapidly cleaved by phosphatase enzymes into estradiol upon administration. Estradiol phosphate is contained within the chemical structures of two other estradiol esters, polyestradiol phosphate and estramustine phosphate, both of which have been marketed for the treatment of prostate cancer.
