Manx cattle became extinct c. 1815. A description of the breed survives along with a record that the Manx people referred to them as Boaghans or Boghans. Thomas Quayle described the Manx breed, just as they were dying out, in his 1812 General View of Agriculture in the Isle of Man:
The Manx sheepdog was a breed of sheepdog from the Isle of Man that is now extinct. Little is known about the breed except that it had a remarkable "ability to 'hould' or separate and immobilise, any sheep which was pointed out". The following extract is believed to have been written by a Ms. A. L. J. Gosset; It continues... It continues...
Manx horse
Manx horses also became extinct c. 1820–1830. Of them Thomas Quayle said,
Manx pig
The Manx pig were known to the locals as 'purrs'. They had completely died long before Thomas Quayle wrote this about them;
Four species of birds that once bred on the Isle of Man have gone extinct locally; of these, the great auk is extinct worldwide. None of these animals were solely native to the Isle of Man. Several other species of mammals, such as the brown bear, wolf and Eurasian beaver, may have once been present in the Isle of Man. However, no evidence has been found of their existence.
JuniperJuniperis communis, became extinct in the 20th century. It suffered a major decline after its uses for firewood and gin making ceased. Climate change is suspected to have made the population that was left infertile.
Trivia
The seabird known as the Manx shearwaterPuffinus puffinus is the only bird that has a name relating to the Isle of Man. However, the bird is found in many parts of the world and is not endemic to the island. It is called the Manx shearwater as the world's largest colony of them was once found on the Calf of Man, a small island off the Isle of Man. This colony was wiped out after longtails were accidentally introduced in the late 18th century. In the late 20th century, these were eradicated and a small colony of 'Manxies' exists on the island once again.
The island's wrens may be a subspecies endemic to the Isle of Man.