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FLT3LG
Fms-related tyrosine kinase 3
ligand
is a
protein
which in
humans
is encoded by the
FLT3LG
gene.
Flt3 ligand is a
hematopoietic
four
helical
bundle
cytokine
. It is
structurally homologous
to
stem cell factor
and
colony stimulating factor 1
. In
synergy
with other
growth factors
, Flt3 ligand stimulates the
proliferation
and
differentiation
of various
blood cell
progenitors
. For example, it is a major
growth factor
stimulating the
growth
of
dendritic cells
.