FRS2
Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene.
FRS2 is an 80 kDa membrane-anchored signal transducing adaptor protein that links specific activated Receptor Tyrosine Kinases to multiple downstream signaling pathways, most notably the MAPK/ERK, PI3K/AKT/mTOR and PLCγ pathways. It is overexpressed and amplified in several cancer types, including prostate cancer.Interactions
FRS2 has been shown to interact with:
