Ferredoxin—NAD(+) reductase
In enzymology, a ferredoxin–NAD+ reductase is an enzyme that catalyzes the chemical reaction:
Thus, the two substrates of this enzyme are reduced ferredoxin and NAD+, whereas its 3 products are oxidized ferredoxin, NADH, and H+. This enzyme participates in fatty acid metabolism.
This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor.
The systematic name of this enzyme is ferredoxin:NAD+ oxidoreductase. There are a variety of names in common use:
- ferredoxin–nicotinamide adenine dinucleotide reductase
- ferredoxin reductase
- NAD+-ferredoxin reductase
- ferredoxin–NAD+ reductase
- ferredoxin–linked NAD+ reductase
- ferredoxin–NAD reductase
When NAD molecule is in its reduced form, the enzyme is referred to as:
- NADH-ferredoxin oxidoreductase
- reduced nicotinamide adenine dinucleotide-ferredoxin
- NADH-ferredoxin reductase
- NADH flavodoxin oxidoreductase
- NADH2-ferredoxin oxidoreductase
Other enzymes in the family include:
- NADH-ferredoxin NAP reductase
- NADH-ferredoxin TOL reductase
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.
