This tour marked the first time that guitarist Glenn Tipton would not perform on a full-length tour after revealing the news that he had been diagnosed with Parkinson's disease on 12 February 2018 and would step down from touring as the disease's progression left him unable to perform the more challenging material. He stated that he was still a member of Judas Priest despite his diagnosis and would not rule out future on-stage appearances. Producer and guitarist Andy Sneap stepped in to perform in his place for the tour. Guitarist Richie Faulkner assured fans that Tipton would perform with the band again. At the 20 March 2018 show in Newark, Tipton joined the band on stage to perform "Metal Gods", "Breaking the Law" and "Living After Midnight", then "Victim of Changes" and "No Surrender" on later dates. He would continue to appear on tour, performing only the encore songs, but would not perform on certain dates, depending on his health. Tipton did not make anymore appearances on the remaining dates of the band's world tour due to his illness, as explained by bassist Ian Hill. After the completion of the world tour, Faulkner thanked fans worldwide for attending their shows, "It's been emotional and amazing to see you all and share in the celebration of heavy metal all around the world. It's been a pleasure and an honour to serve. See ya on the next one RHRF DOTF."
Shortly into the song "Judas Rising" at the 25 May 2019 show in Rosemont, Rob Halford kicked a cell phone out of a fan's hands in frustration as the fan had the phone light on while filming the show, causing difficulty on his performance. Halford explained in a statement soon after that fans are free to capture footage of their shows, "However if you physically interfere with The Metal God's performance you now know what will happen." Uriah Heep vocalist Bernie Shaw stepped in to defend Halford and said that he understood his frustration, but felt that he took it "a little bit too far", and opined that his "space was invaded." He thought that Halford "overreacted — but I can sure understand where it came from."
The 2018 to early 2019 setlist featured material from Firepower, fan favourites and even material that was not performed in decades such as "Bloodstone", "Some Heads Are Gonna Roll", "Tyrant", "Night Comes Down", "Delivering the Goods" and "Killing Machine". Judas Priest introduced the song "Saints in Hell", which was never performed in the band's live shows. The third North American portion of the tour in 2019 featured an updated stage appearance and a brand new setlist featuring other tracks from Firepower and other various songs, and even a few more songs that were not played in decades such as "Out in the Cold", "All Guns Blazing" and "Hot Rockin'". The band introduced another song, " Chains", which was also never performed in the band's live shows.