Roma started his career in the youth teams of Lazio. He was the third goalkeeper behind Luca Marchegiani and Fernando Orsi before leaving the club to play for clubs in Serie B and Serie C1. In 1999, he was signed by the Serie A side Piacenza as part of Simone Inzaghi's deal, replacing Valerio Fiori as the first choice in his role, but the team was relegated at the end of season.
In 2001, he was signed by Monaco, then coached by Didier Deschamps, where he was the first choice goalkeeper ahead of Tony Sylva and Stéphane Porato until the 2008–09 season, when he lost his place to Stéphane Ruffier. He was also in the squad that played the 2004 UEFA Champions League Final. During his stay at Monaco, he only missed three months in the 2005–06 season due to injuries, and a shoulder injury ruled him out of the second half of the 2001–02 season in February 2002. During his career at Monaco, Roma rejected an opportunity to join English side Arsenal in order to sign a new contract with the club.
On 12 August 2009, Roma signed a one-year contract with Milan to replace Zeljko Kalac, who was released from the club by mutual consent. Upon joining Milan, Roma cited joining the club as a dream come true, and Roma was expected to compete for the starting position with Marco Storari while Christian Abbiati and Dida were recovering from injury. However, Milan manager Leonardo preferred Storari and, after his return from injury, Dida. In January 2010, Storari left for Sampdoria and Abbiati recovered from injury, making Roma the third-choice goalkeeper. At the end of the season, his contract was extended to an undisclosed length. In 2011, Roma started in goal in two matches in the Coppa Italia against Bari and Sampdoria, earning a clean sheet against Bari and conceding only one goal away against Sampdoria. On 17 May 2011, Milan announced Roma extended his contract for an additional year. On 13 May 2012, Roma announced he had played his last match for Milan.
Return to Monaco
On 2 August 2012, Roma signed for Monaco on a one-year deal on a free transfer. Following Monaco's promotion to Ligue 1, Roma made his first appearance in his second spell, where he came on as a substitute for Martin Sourzac in the second half, as Monaco won 2–1 against Tours. After making one appearance, Roma signed a contract extension. At the end of the season, he announced his retirement.
