Folate-binding protein
Folate-binding protein are proteins that bind folate, typically the folate receptors and reduced folate carrier.
FBP can be a marker for ovarian cancer.
FBP can be measured to help in tumour classification to aid treatment, as it is over-expressed in more than 90% of ovarian and endometrial cancers, as well as 20-50% of breast, lung, colorectal, and renal cell carcinomas. FBP has very limited tissue distribution and expression in non-malignant tissue, making it a good immunotherapy target.FBP can refer to protein used to do folic acid assays.
