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Fosfluconazole
Fosfluconazole
is a
water-soluble
phosphate
prodrug
of
fluconazole
— a
triazole
antifungal drug
used in the
treatment
and
prevention
of
superficial
and
systemic
fungal infections
.
The phosphate
ester bond
is
hydrolyzed
by the
action
of a
phosphatase
— an
enzyme
that removes a
phosphate group
from its
substrate
by hydrolyzing
phosphoric acid monoesters
into a
phosphate ion
and a
molecule
with a
free
hydroxyl group
.
