François-Joseph
François-Joseph is a given name, and may refer to:
- François-Joseph Amon d'Aby, Ivoirian playwright and essayist
- François-Joseph de Beaupoil de Sainte-Aulaire, French poet and army officer
- François-Joseph Bélanger, French architect and decorator
- François-Joseph Bérardier de Bataut, French teacher, writer and translator
- François-Joseph Bissot, Canadian merchant, navigator and a co-seigneur of Mingan; son of François Byssot de la Rivière
- François-Joseph Bressani, Jesuit priest
- Général François-Joseph Chaussegros de Léry, Canadian Engineer-in-Chief and Commander-in-Chief of Napoleon's Armies Armies in Holland
- François-Joseph d'Offenstein, French general and military commander
- François-Joseph de Champagny, French author and historian
- François-Joseph Duret, French sculptor
- François-Joseph Fétis, Belgian musicologist, composer, critic and teacher
- François-Joseph Hunauld, French anatomist
- François-Joseph Laflèche, Canadian politician
- François-Joseph Navez, Belgian neo-classical painter
- François-Joseph Talma, French actor
- Nzanga Mobutu , politician in the Democratic Republic of the Congo