Francis Blake
- Blake (surname)
- Blake and Mortimer
- Francis Blake (1638–1718)
- Francis Blake (telephone)
- Francis Claude Blake
- Francis Gilman Blake
- Sir Francis Blake, 1st Baronet, of Tillmouth Park
- Sir Francis Blake, 1st Baronet, of Twizell Castle
- Sir Francis Blake, 2nd Baronet, of Tillmouth Park
- Sir Francis Blake, 2nd Baronet, of Twizell Castle
- Sir Francis Blake, 3rd Baronet, of Twizell Castle
