Francis Osborne (disambiguation)

• D'Arcy Osborne, 12th Duke of Leeds
• Frances Osborne
• Francis C. Osborn Sr.
• Francis D'Arcy-Osborne, 7th Duke of Leeds
• Francis Osborne
• Francis Osborne (North Carolina politician)
• Francis Osborne, 1st Baron Godolphin
• Francis Osborne, 5th Duke of Leeds
• Frank Osborne (disambiguation)