Prior to becoming a politician, McGuire was a respected journalist and the winner of two Walkley Awards for excellence in journalism. The first was in 1993, when he won the investigative report award for a segment called 'Deadly Force' that screened on ABC TV's Four Corners program in May 1992. In 2007, he won with fellow journalist Adam Shand, for a report on Nine Network's Sunday program, called "Force within a force" which was about alleged police corruption. McGuire's experience includes being a news reporter at the Melbourne Herald ; reporter/producer/deputy chief-of-staff on Ten News. He was a current affairs investigative and political reporter on The 7.30 Report and on Four Corners.
Local government taskforce
In 1999, McGuire was the founding chair of the City of Hume's Hume Safe City Taskforce, and served until 2004. He accepted the position pro bono on the condition he was given sufficient independence to establish the Global Learning Village – a model that coordinated local, state and federal governments, business, community groups and academic institutions, to deliver better results for communities.
Political career
Frank McGuire is Victoria's first Parliamentary Secretary for Medical Research and is also Parliamentary Secretary for Small Business and Innovation. Frank has driven Victoria's medical research strategy since December 2014 to lead Australia in a bigger and bolder fashion globally. He called for a partnership with America in President Barack Obama's ‘Moonshot’ quest to cure cancer, leading to US Vice President, Joe Biden's visit to Melbourne for the opening of the billion dollar jewel in Australia's medical research crown, the Victorian Comprehensive Cancer Centre. Frank has paved the way for other international collaborations and assisted Health Minister, Jill Hennessy in developing Victoria's International Health Strategy, Partnering for a Healthy and Prosperous Future 2016–2020, and Victoria's Health and Medical Research Strategy, Healthier Lives, Stronger Economy 2016–20, designed to create economic benefit through global leadership in healthcare, health education, aged care and medical research while creating jobs and economic growth by boosting investment, industry development and exports. Frank launched the Science, Medical Research and Technology panel in 2016, an initiative designed to leverage investment and partnerships to transfer discoveries from benchtop to business. In his first term, Frank was deputy chair of the Victorian Parliamentary inquiry that produced the landmark report, Betrayal of Trust, into the handling of child abuse by religious and other non-government organisations in 2013. He also co-chaired Parliament's Economic Development, Infrastructure and Outer Suburban/Interface Services Committee. Frank was nominated for the international Metropolis Award for innovation in 2011 for his model for smarter, healthier, better connected and sustainable communities, the Global Learning Village, supported by Silicon Valley leaders Microsoft, Intel and Cisco Systems. His Walkley Awards were for investigative journalism, for a body of work stretching from Ten News to current affairs at the ABC's 7.30 Report and flagship, Four Corners in 1993 and an exposé for the Nine Network's Sunday in 2007. He is also the recipient of a Human Rights Media award. Frank is a fellow of Leadership Victoria and in 2016 published Creating Opportunity: Postcodes of Hope, a blueprint for cultural, generational and systemic change delivering lifelong learning, economic development and jobs.
McGuire lives in the Melbourne suburb of Fitzroy, but was brought up in Broadmeadows. Like his younger brother, media personality and Collingwood Football Club president, Eddie McGuire, Frank McGuire was educated at Christian Brothers College in St Kilda on a scholarship. Unlike his brother, Frank McGuire is a keen follower of AFL football team, Essendon. McGuire has three children.