Born in Torgau, he succeeded his father as elector in 1486; in 1502, he founded the University of Wittenberg, where Martin Luther and Philip Melanchthon taught., minted ca. 1507–25. Both the obverse and the reverse bear a coat of arms. Frederick was among the princes who pressed the need of reform upon Holy Roman Emperor Maximilian I, and in 1500, he became president of the newly-formed council of regency. His court painter from 1504 was Lucas Cranach the Elder. Frederick was Pope Leo X's candidate for Holy Roman Emperor in 1519; the Pope had awarded him the Golden Rose of virtue on 3 September 1518 in an effort to persuade him to accept the throne. However, Frederick helped secure the election of Charles V by agreeing to support Charles and to convince his fellow electors to do the same if Charles repaid an outstanding debt to the Saxons dating to 1497. Frederick ensured that Martin Luther would be heard before the Diet of Worms in 1521 and secured an exemption from the Edict of Worms for Saxony. Frederick collected many relics in his castle church; his inventory of 1518 listed 17,443 items, including a thumb from St. Anne, a twig from Moses' burning bush, hay of the holy manger, and milk from the Virgin Mary. Money was paid in order to venerate these relics and thus escape years in purgatory. A diligent and pious person who rendered appropriate devotion to each of these relics could merit 1,902,202 years worth of penance. Two years later, the collection exceeded 19,000 pieces. He protected Luther from the Pope's enforcement of the edict by faking a highway attack on Luther's way back to Wittenberg, abducting and then hiding him at Wartburg Castle after the Diet of Worms. Frederick died unmarried at Lochau, a hunting castle near Annaburg, in 1525 and was buried in the Schlosskirche at Wittenberg with a grave by Peter Vischer the Younger. He was succeeded by his brother Duke John the Steadfast'' as Elector of Saxony.
Issue of conversion in 1525
Frederick III was a lifelong Roman Catholic, but he might have converted to Lutheranism on his deathbed in 1525 depending on how his receiving of a Protestant communion is viewed. He leaned heavily towards Lutheranism throughout his later years, guaranteeing safety for his subject and Protestant reformer Martin Luther when he was tried for heresy and excommunicated by the Pope. Frederick III took communion as outlined in Lutheranism on his deathbed. That can be seen as a conversion to Lutheranism, although he never officially or clearly indicated that he converted. By the time of his death, he was proclaimed to have "converted to the evangelical faith" and Saxony was now "evangelical". He protected Martin Luther and allowed Lutheranism to flourish in his realm, protecting him from the Holy Roman Emperor. His successor, John, Elector of Saxony, had been Lutheran even before he became elector. John made the Lutheran church the official state church in Saxony in 1527.