Fujimoto–Belleau reaction
The Fujimoto–Belleau reaction is a chemical reaction that forms cyclic α-substituted α,β-unsaturated ketones from enol lactones. The reaction is named after the two chemists George I. Fujimoto and Bernard Belleau.
The reaction is a Grignard reaction, followed by a H-shift, an enol-keto tautomerisation and an Aldol addition reaction. The last step is an elimination reaction with an E1CB mechanism.
