Up to four players can compete in two different game modes: "Tournament" or "Mini-Game Frenzy". Mini-Game Frenzy is the simpler of the two, involving players selecting individual mini-games while an ongoing tabulation of wins per player is maintained. In contrast, the Tournament mode is the coregame mode, where players attempt to earn the highest number of points after playing through two or more play zones. 22 different game modes.
During game setup, players choose from one of six characters, with extra player slots being filled by computer AI. The number of zones to play through is also selected. The exact zones which are used during play are determined randomly, in addition to the order in which the zones are played. Unlike other party games such as the Mario Party series or Sonic Shuffle, Fuzion Frenzy has no overarching game board, rather, players proceed from one random mini-game to another, and from zone to zone, in an order determined without player input. The traversal between zones is depicted as a route on a map which never crosses itself, limiting the possible transitions between zones. In each zone, three random mini-games are played. For mini-games which are team games, players are paired randomly. Some mini-games are timed, and some are not. Mini-games that are timed usually have a time limit of 60 seconds or 90 seconds to play, though some even have a time limit of 2 minutes. Most un-timed mini-games have a "last player standing wins" rule. At the conclusion of each mini-game, players are awarded a number of orbs proportional to their final standing in the event. If there is a tie for 1st, 2nd, or 3rd place; the orbs are split proportionally. Regardless, the orbs accumulate throughout the zone. Once a new zone begins, the players start from scratch. Once the third mini-game is finished, the zone ends with the special "Fuzion Frenzy" mini-game. Each player must decide whether to bank their orbs, or put them into play for this Fuzion Frenzy. Each player may risk any or all of their orbs, but must risk at least 3 orbs. The players are then put in an arena, where glowing orbs appear at random. Some of these orbs are colorless, while others are the colored orbs wagered by the players. Within 80 seconds, each player attempts to grab orbs and deliver them to the goal zones in order to score points. A player can only pick up colorless orbs or orbs that match his color. However, once a player picks up an orb, it becomes colorless, and others players can steal it by attacking the carrier. Players can carry more than one orb at once, and delivering more than one orb at a time provides a score bonus. When the 80-second timer ends, the points earned in the Fuzion Frenzy are added to a player's total, and it is this total which actually determines the winner of the zone. Thus, a player who didn't finish first after the three mini-games may still win the overall zone if he performs well in the Fuzion Frenzy. If there is a tie between two or more of the players at the end of the final Fuzion Frenzy, a tie-breaker mini-game is played to determine the winner.
