GABA receptor antagonist


GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used for counteracting overdoses of sedative drugs.
Examples include bicuculline, securinine and metrazol, and the benzodiazepine GABAA receptor antagonist flumazenil.
Also the antibiotic , thujone, ginkgo biloba, kudzu and muira puama may have properties of GABAA receptor antagonism.