GCS1


Mannosyl-oligosaccharide glucosidase is an enzyme that in humans is encoded by the MOGS gene.
Glucosidase I is the first enzyme in the N-linked oligosaccharide processing pathway. GCS1 cleaves the distal alpha-1,2-linked glucose residue from the Glc-Man-GlcNAc oligosaccharide precursor. GCS1 is located in the lumen of the endoplasmic reticulum.
GCS1 may also refer to "generative cell specific 1", also called HAP2, a gene of lower eukaryotes which is thought to be responsible for gametes fusion.