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GPR143
G-protein coupled receptor
143
is a
protein
encoded by the
GPR143
gene
in
humans
.
Ocular albinism type 1
protein is a conserved
integral membrane protein
with seven
transmembrane domains
. It is expressed in
the eye
and
epidermal
melanocytes
.
The GPR143 gene is
regulated
by the
Microphthalmia-associated transcription factor
.
L-DOPA
is an
endogenous ligand
for OA1.
Interactions
GPR143 has been
shown
to
interact
with
GNAI1
.