Brush was born in Brooklyn, New York on December 15, 1831. He began his studies at Yale in 1848 with courses from Benjamin Silliman, Jr. and John Pitkin Norton on practical chemistry and agriculture. He also studied chemistry, metallurgy and mineralogy. He left in 1850 to work with Benjamin Silliman, Jr. but received his Ph.D. from Yale in 1852 by special examination. From 1852 to 1855, Brush worked and studied at the University of Virginia and in Munich and Freiberg. He returned to Sheffield in 1855 to join the faculty as professor of Metallurgy and later of Mineralogy. Brush had begun acquiring an extensive research collection of minerals. He was appointed the first curator of the Peabody Museum of Natural History's mineral collection. He was a member of the Connecticut Academy of Arts and Sciences. In 1872, he became the first director of Sheffield, where he also supervised mineralogy. He served as the president of the American Association for the Advancement of Science in 1881. He published extensively in the American Journal of Science and other journals. He also published a Manual of Determinative Mineralogy. In 1898, Brush retired from teaching and administration at Sheffield. He continued serving at the school, however, as secretary, treasurer and president of the board, until 1911. In 1904, Brush donated his collection of minerals, along with funds for their maintenance, to Sheffield. Originally housed in Hammond Hall at Yale, the Brush Collection is now administered by the Division of Mineralogy at the Yale Peabody Museum. Brush died in New Haven on February 5, 1912. The mineral brushite was named in his honor by G. E. Moore.
Literature
On the Chemical Composition of Clintonite, Second Series, Vol. XVIII, №54- Nov. 1854
On Chalcodite. Am. Journal of Science and Arts, Vol.25, p. 1-4, March 1858
Mineralogical notices. Am. Journal of Science and Arts, Vol.26, p. 64-70,1858
* Gieseckite?
* Compact Pyrophyllite
* Unionite
* Feldspare from the Danbureite locality
On Boltonite. Am. Journal of Science and Arts, Vol.27, p. 395-398, May 1859