Hostilities between Britain and France were soon renewed with the outbreak of the Seven Years' War in 1756. The 35th Regiment was deployed to America, where Monro relieved Lieutenant-Colonel William Eyre as commander of Fort William Henry in the Province of New York. That summer, the French General Louis-Joseph de Montcalm led a force of 8,000 French and Indian troops in a weeklong Siege of Fort William Henry. Effectively cut off from the main British force, commanded by General Daniel Webb, the 1,500 man British garrison stood little chance of holding the fort once the French began formal siege operations on 3 August. Monro was forced to open negotiations with Montcalm on 9 August. Monro's tenacious defence of the fort won him generous terms of surrender from Montcalm. The British were accorded the full honours of war, being allowed to keep their colours, muskets, and a single symbolic cannon. The garrison would be paroled and allowed to march to the British-held Fort Edward, about away. However, it was not to be. As Monro led his garrison from Fort William Henry the next day, the Indian warriors attacked the British soldiers, killing approximately 185 dead. Monro actually survived the massacre, but he died suddenly in Albany just three months later on 3 November 1757.
In popular culture
Colonel Munro is portrayed in James Fennimore Cooper's story The Last of the Mohicans, in which he is the father of two daughters, Alice and Cora. In the story, he plays a similar role as he did in history, leading the defense of Fort William Henry. In the blockbuster 1992 film adaptation, he is portrayed by Scottish actor Maurice Roëves, in which he is portrayed as being killed in the massacre by Montcalm's Indian allies, the leader of whom cuts his heart out as revenge for Monro killing his family. He is also portrayed in the 1920 silent film by James Gordon, in the 1932 version by Edward Hearn, in the 1936 version by Hugh Buckler and in the 1965 version by Paul Muller and in the 1968 version by Otto Ambros. Monro is also portrayed as a supporting character in the 2014 action-adventure video gameAssassin's Creed Rogue. He is shown to be a noble character, seeking to help the people of New York City recover from the gang violence and the disrepair of the city. He is a member of the Templar Order and assists Christopher Gist and the protagonist Shay Patrick Cormac until he is killed by Assassin Liam O'Brien in Albany after the fall of Fort William Henry. He is voiced by Graham J. Cuthbertson.