Gilbert Talbot was born in 1606, younger son of Sharington Talbot and his first wife Elizabeth Leighton. The family was related to the Talbot Earls of Shrewsbury, and originated from Salwarpe, Worcestershire; they acquired Lacock Abbey, Wiltshire through his grandmother, Olive. The Talbots were a long-lived family; Olive died in 1646, at the age of 97, both Gilbert and his elder brother Sharington lived into their 80s, as did many other relatives. He also had four half-brothers from his father's second marriage to Mary Washburn; George, Edward, who was killed in the First English Civil War, William, and Francis.
Career
He studied at Christ Church, Oxford, where he was awarded BA in 1626, then Lincoln College, Oxford, where he gained an MA in 1628. He was a fellow of All Souls College, Oxford from 1629 to 1634. In 1634, he joined the English mission to the Republic of Venice, where he served as Secretary, Resident, then lastly Envoy. During the 1642–1646 First English Civil War, he tried to persuade the Venetians to provide financial assistance to Charles I, while devising schemes for confiscating Parliamentarian merchant ships in Constantinople. However, given London's importance in the Levant trade, the Venetians never seriously contemplated this. He returned to England in January 1645, and made his way to Charles' war-time capital of Oxford, where he was knighted. At the beginning of 1645, the Royalists still controlled most of the West Country, Wales, and counties along the English border. Despite his lack of military experience, Talbot was appointed governor of Tiverton Castle, in Devon; his elder brother, Colonel Sharington Talbot, commanded the Royalist garrison at Lacock Abbey, Wiltshire.
A series of victories by the New Model Army under Sir Thomas Fairfax meant by mid-July the Royalists faced defeat. Tiverton fell on 19 October; taken prisoner, Talbot was exchanged, and made his way to Oxford, which surrendered in June 1646, bringing the First Civil War to an end. Under the Articles of Surrender, signed on 20 June, he was allowed to return home, without having to 'compound', or pay a fine. He retired to Dartmouth, and took no part in the 1648 Second English Civil War; in 1650, he was arrested on suspicion of conspiring to restore Charles II, and held in Gloucester gaol. On his release, he went abroad to join the exiled court around Charles II, and was made a Gentleman Usher of the Privy Chamber. During this period, he became part of the faction opposed to the Earl of Clarendon, centred around the Duke of Ormond; at the 1660 Restoration, Ormonde gained him an appointment as Master of the Jewel House. During the Second Anglo-Dutch War, in September 1664, he was sent as special envoy to Denmark. He acted as intermediary in secret discussions between Charles and Frederick III in August 1665, over an attack on a Dutch merchant fleet taking shelter in the Norwegian port of Bergen. Although Frederick was a Dutch ally, he agreed to order his garrison not to fire on the English squadron, in return for a share of the profits. In the event, they opened fire, and Sir Thomas Teddeman was forced to retreat; Sir Gilbert was blamed for the confusion and recalled in April 1666. On his return, he was elected to fill a recent vacancy as Member of Parliament for Plymouth in 1666. He had been elected as a founding member of the Royal Society; in 1667, he presented a paper on Swedish stone, which affords sulphur, vitriol, allum and minium. When Parliament was dissolved in 1678, he did not stand again, and retired from active politics. As a long-time Stuart loyalist, he was appointed Deputy Lieutenant of Wiltshire by James II in 1688. After the November 1688 Glorious Revolution, both he and his nephew Sir John Talbot refused to swear allegiance to the new regime of Mary II and William III, and lost their positions as a result. In his later years, he lived at Lacock Abbey, where he died in 1695, and later buried in the family vault at Salwarpe. He had never married.