Giuffrè

• Aldo Giuffrè, Italian film actor and comedian who appeared in over 90 films between 1948 and 2001
• Antonino Giuffrè, Italian mafioso from Caccamo in the Province of Palermo, Sicily
• Carlo Giuffrè, Italian film actor
• Gaetano Giuffrè, Italian-Greek composer
• Jimmy Giuffre, American jazz composer, arranger and saxophone and clarinet player
• Matthew Giuffre, Canadian squash player