Manfredi was born 17 March 1828 in Cortemaggiore, at the time part of Duchy of Parma and Piacenza. His parents were Domenico and Paola Enrichetta Fogliazzi Manfredi and he had a brother, Enrico, and a sister, Maria Anna. Leaving his home, Manfredi attended a Jesuit high school in Piacenza. He received a law degree from the University of Parma in 1849.
Career
Manfredi worked in a law office beginning in 1846. Over the next few years he became interested in politics and expressed his views about democratic philosophies in the newspaper Il Tribuno del popolo and in pamphlets. He also wrote about anti-clericalism and Jacobinism. See alsoRevolutions of 1848. Having received his law degree, he began practicing as an attorney in 1849. Beginning in November 1851, he tried both criminal and civil cases in Piacenza. He was an investigating officer in 1853 at the Indirect Tax Administration of the Ministry of Finance of Parma. Due to the things that Manfredi had written beginning in 1848, he was banned from practicing law by Charles III, Duke of Parma. After his death, Louise Marie, the Regent Duchess, reopened the University of Parma. From 1855 to 1859, Manfredi taught law at the University of Parma. He was involved in the Unification of Italy, working with a friend and leader of the unification movement, Giuseppe La Farina. During the War of 1859, he coordinated the volunteers and kept in contact with La Farina, Manfredo Fanti, and Luigi Carlo Farini. During the summer of 1859, he held a number of political offices, including Member of the Provisional Government of Piacenza, administrator of the province of Parma, a Member of the :it:Assemblea dei rappresentanti del popolo|Assembly of People's Representatives in Parma, and Provisional Governor of Parma and Piacenza. See also Kingdom of Italy. In 1862, he became Deputy Attorney General in the PerugiaCourt of Appeals. Three years later, he was Advocate General in Perugia. He was also made Attorney General of Catania in 1868, and then served in that role in Bologna in 1869, in Rome in 1876. He was also the first president of the Court of Appeal of Ancona in 1876. On 20 November 1876, he took the oath as Senator of the kingdom of Italy. From 1881 until 1907, he was the Attorney General at the Supreme Court in Florence. On 28 December 1907, he was elected vice-president of the upper house of the Senate. From 20 March 1908 until his death, he was the president of the Italian Senate, spanning three terms. Over his career, he was a member of the governing Council of the Order of Lawyers of Piacenza, the Italian Geographical Society, and the National Committee for the history of the Italian unification.
He was married twice. He married Paolina Giuditta Bertani in 1852 and they had six children, Philip, Clara, Vittorio Emanuele Manfredo, Ernestino and Leopold. Paolina died in April 1877, and he subsequently married Countess Maria Carmela Giannerini, with whom he had four children, Corrado, Marcello, Anna, and Luis. Manfredi died on 11 June 1918 in Rome. In the commemoration by the Senate, he was described as follows, — which roughly translates to "We remember the noble and dear countenance, an affable manner, the solemn word, an affectionate heart, the candid and pure soul, ardent love of country."
