Glucosidases


Glucosidases are the glycoside hydrolase enzymes categorized under the EC number 3.2.1.

Function

α-glucosidases are enzymes involved in breaking down complex carbohydrates such as starch and glycogen into their monomers
They catalyze the cleavage of individual glucosyl residues from various glycoconjugates including alpha- or beta-linked polymers of glucose. This enzyme convert complex sugars into the simpler one.

Members

Different sources include different members in this class. Members marked with a "#" are considered by MeSH to be glucosidases.

Clinical significance

They are targeted by alpha-glucosidase inhibitors such as acarbose and miglitol to control diabetes mellitus type 2.