Group II pyridoxal-dependent decarboxylases


In molecular biology, group II pyridoxal-dependent decarboxylases are family of enzymes including aromatic-L-amino-acid decarboxylase , which catalyses the decarboxylation of tryptophan to tryptamine, tyrosine decarboxylase, which converts tyrosine into tyramine and histidine decarboxylase, which catalyses the decarboxylation of histidine to histamine.
Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group II includes glutamate, histidine, tyrosine, and aromatic-L-amino-acid decarboxylases.