Growth hormone secretagogue
Growth hormone secretagogues or GH secretagogues are a class of drugs which act as secretagogues of growth hormone. They include agonists of the ghrelin/growth hormone secretagogue receptor, such as ghrelin, pralmorelin, GHRP-6, examorelin, ipamorelin, and ibutamoren, and agonists of the growth hormone-releasing hormone receptor, such as growth hormone-releasing hormone , CJC-1295, sermorelin, and tesamorelin. Many also induce the secretion of insulin-like growth factor 1, as well as of other hypothalamic-pituitary hormones such as prolactin and cortisol. The main clinical application of these agents is the treatment of growth hormone deficiency. They also see black market use, similarly to anabolic steroids, for bodybuilding purposes.
