HIF prolyl-hydroxylase inhibitor


Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors also known as Hypoxia-Inducible Factor stabilizers are members of a class of new drugs that act by inhibiting prolyl hydroxylase which is responsible to break down the hypoxia-inducible factor under normoxic conditions.
they are being investigated for treatment of anemia, chronic kidney disease, cancer, and for their effects on heart tissue and others.
Research conducted in mice suggests that they may increase hippocampal memory by increasing erythropoietin expression.
They act by inhibiting HIF prolyl-hydroxylase enzymes.