HIV salivary gland disease


Human immunodeficiency virus salivary gland disease, is swelling of the salivary glands and/or xerostomia in individuals infected with human immunodeficiency virus.

Signs and symptoms

HIV-SGD may be the presenting sign of HIV infection. There may also be xerophthalmia and arthralgia, similar to Sjögren syndrome.

Epidemiology

HIV-SGD is more prevalent in HIV positive children than HIV positive adults, at about 19% and 1% respectively. Unlike other oral manifestations of HIV/AIDS such as Kaposi sarcoma, oral hairy leukoplakia and oral candidiasis, which decreased following the introduction of highly active antiretroviral therapy, HIV-SGD has increased.