Haplogroup L4 (mtDNA)
Haplogroup L4 is a human mitochondrial DNA haplogroup. It is a small maternal clade primarily restricted to Africa.
L4 is important in East Africa and Horn of Africa. The highest frequencies are in Tanzania among the Hadza at 60-83% and Sandawe at 48%.
It has two branches, L4a and L4b. Subgroup L4a was formerly called L7 and considered a separate subclade of L3'4'7. It has been recognized as a subclade of L4, with L3 as its outgroup by Behar et al..
The parent clade L3'4 is to have emerged at 106-66 kya.
L4 is not much later than this, estimated at 87 kya by Fernandes et al..Phylogeny
The following phylogeny is based on van Oven and Kayser.
- L3'4
- *L4
- ** L4a , mutations: 195C, 3357, 5460, 10373, 11253, 11344, 11485, 12414, 13174, 14302, 16260.
- ***L4a1
- ****L4a1a
- ***L4a2
- **L4b, mutations: 709, 3918.
- ***L4b1
- ***L4b2
- ****L4b2a
- *****L4b2a1
- *****L4b2a2
- ******L4b2a2a
- ******L4b2a2b
- ****L4b2b