Morowitz was born in Poughkeepsie, New York. He received a B.S. in physics and philosophy in 1947, an M.S. in physics in 1950, and a Ph.D. in biophysics in 1951, all from Yale University. Morowitz was a professor in the department of molecular biophysics and biochemistry at Yale from 1955 to 1987, also serving as the Master of Pierson College from 1981 to 1986. He spent the rest of his career on the faculty at George Mason University, which he joined in 1988 as Clarence Robinson Professor of biology and natural philosophy. He served as the founding director of the Krasnow Institute for Advanced Study at George Mason from 1993 to 1998. Morowitz was closely associated with the Santa Fe Institute since 1987, where he was Chairman Emeritus of the Science Board. He also served as the founding editor of the journal Complexity. In the 1990s he contributed a monthly column on science and society to Hospital Practice. Morowitz was a longtime consultant for NASA, and served on the committees that planned the quarantine procedures for Apollo 11 and the biology experiments the Viking probe carried to the surface of Mars. He was a member of the science advisory committee for Biosphere 2 in Oracle, Arizona, which, at 3.14 acres, is the largest enclosed ecosystem ever built. Some leading biophysicists have suggested that Morowitz may have discovered a "fourth law of thermodynamics" when, in 1968, he found that, "in steady state systems, the flow of energy through the system from a source to a sink will lead to at least one cycle in the system." Eric D. Schneider, for example, says, "Morowitz's cycling theorem is the best candidate for a fourth law of thermodynamics."
Morowitz's book Energy Flow in Biology laid out his central thesis that "the energy that flows through a system acts to organize that system," an insight later quoted on the inside front cover of The Last Whole Earth Catalog. He was a vigorous proponent of the view that life on earth emerged deterministically from the laws of chemistry and physics, and so believed it highly probable that life exists widely in the universe. In 1983, he testified at "McLean v. Arkansas" that creationism has no scientific basis and so should not be taught as science in public schools. His work is sometimes associated with the Gard model of evolutionary biology
Publications
Proceedings of the First National Biophysics Conference. Yale University Press, 1959, Morowitz, H.J. and Quastler, H., Editors.
Life and the Physical Sciences: Introduction to Biophysics. HoltRinehart and Winston, Inc., 1963, Morowitz, H.J.
Theoretical and Mathematical Biology. Blaisdell Publishing Co., 1965, Waterman, T. and Morowitz, H., Editors.
Energy Flow in Biology. Academic Press, 1968, Morowitz, Harold J.
Entropy for Biologists. Academic Press, 1970, Morowitz, Harold J.
Life on the Planet Earth. W. W. Norton & Co., 1974, Morowitz, H.J. and Morowitz, L.S.
Ego Niches: An Ecological View of Organizational Behavior. Ox Bow Press, 1977, Morowitz, Harold J.
Foundations of Bioenergetics. Academic Press, 1978, Morowitz, Harold J.
The Wine of Life & Other Essays on Societies, Energy, & Living Things. St. Martin's Press, 1979, Morowitz, Harold J.
Mayonnaise and The Origin of Life: Thoughts of Minds and Molecules. Charles Scribner's Sons, 1985, Morowitz, Harold J.
