Hemoglobin A2


Hemoglobin A2 is a normal variant of hemoglobin A that consists of two alpha and two delta chains and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.
HbA2 exists in small amounts in all adult humans and is approximately normal in people with sickle-cell disease. Its biological importance is not yet known.