Hiss (surname)

• Alger Hiss, U.S. State Department employee and an accused Soviet spy
• Anna Hiss, 20th-Century American professor of physical education
• Arlene Hiss, American former race car driver and schoolteacher
• Donald Hiss, younger brother of Alger Hiss
• Mike Hiss, former driver in the USAC Championship Car series
• Priscilla Hiss, a 20th-century American teacher and book editor
• Yehuda Hiss, chief pathologist at the Abu Kabir Institute of Forensic Medicine